Cardiac Resynchronization Therapy in Heart Failure Management
Abstract
Heart failure (HF) is a worldwide health problem with high prevalence rate. The prevalence is over 23 million worldwide. It is a chronic disease characterized by the inability of the heart to pump an adequate amount of blood to achieve the demand of the different organ systems and/or doing so at increased filling pressures. Despite many recent advances in medication, the rate of people with HF is rising. This health challenges need to be answered properly. One of the new important treatment for HF is cardiac resynchronization therapy (CRT). Many patients with HF also have an abnormality of the heart’s electrical system resulting in asynchronous contraction pattern of heart muscle.The ultimate goal of CRT is to restore synchrony of the heart rhythm in HF patients. CRT implantation in heart failure patients with proper indications like wide QRS complexes, low left ventricular ejection fraction (LVEF), and left bundle branch block (LBBB) has been proved to reduce morbidity, mortality, and also improve symptoms and quality of life (QoL).
Downloads
Download data is not yet available.
References
1. Nasif, M, Alahmad A. Congestive heart failure and public health. Bioepidemiology (article online). (Cited 2015 May 22). Available from http://www.cwru.edu/med/epidbio/mphp439/CongHeartFail.pdf
2. Shea JB, Sweeney MO. Cardiac resynchronization therapy: a patient’s guide. Circulation. 2003;108:e64-6.
3. Bui AL, Horwich TB, Fonarow GC. Epidemiology and risk profile of heart failure. Nat Rev Cardiol. 2011; 8(1):30-41.
4. Washington Heart Rhythms Associates. CRT Figures 1 and 2 (cited 2015 May 22). Available from http://www.washingtonhra.com/pacemakers-icds/cardiac-resynchronization-therapy-crt.php
5. Budzikowski AS, Gabriels JK. Cardiac resynchronization technique. Medscape (article online). 2014. (Cited 2015 May 22). Available from http://emedicine.medscape.com/article/1839506-technique
6. Brignole M, Auricchio A, Baron-Esquivias G, Bordachar P, et al. 2013 ESC guidelines on cardiac pacing and cardiac resynchroniztion therapy. Eur Heart J. 2013;34:2281-2329.
7. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, Tavazzi L. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005; 352:1539-49.
8. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, Carson P, DiCarlo L, DeMets D, White BG, DeVries DW, Feldman AM. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004; 350:2140-50.
9. Cazeau S, Leclercq C, Lavergne T, Walker S, Farma C, Linde C, Garrigue S, Kappenberger L, Haywood GA, Santini M, Baileul C, Daubert JC. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Engl J Med. 2001; 344:873-80.
10. Auricchio A, Stellbrink C, Butter C, Sack S, Vogt J, Misier AR, Bocker D, Block M, Kirkels JH, Kramer A, Huvelle E. Clinical efficacy of cardiac resynchronization therapy using left ventricular pacing in heart failure patients stratified by severity of ventricular of conduction delay. J Am Coll Cardiol 2003; 42:2109-16.
11. Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E, Kocovic DC, Packer M, Clavell AL, Hayes DL, Ellestad
M, Trupp RJ, Underwood J, Pickering F, Truex C, McAtee P, Messenger J. Cardiac resynchronization in chronic heart failure. N Engl J Med. 2002; 346:1845-53.
12. Moss AJ, Hall Wj, Cannom DS, Klein H, Brown MW, Daubert JP, Estes NA 3rd, Foster E, Greenberg H, Higgins SL, Pfeffer MA, Solomon SD, Wilber D, Zareba W. Cardiac-resynchronization therapy for the prevention of heart failure events. N Engl J Med. 2009; 361:1329-38.
13. Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S, Hohnloser SH, Nichol G, Birnie DH, Sapp JL, Yee R, Healey JS, Rouleau JL. Cardiac-resynchronization therapy for mild-to-moderate heart failure. N Engl J Med. 2010; 363:2385-95.
14. Linde C, Abraham WT, Gold MR, ST John Sutton M, Ghio S, Daubert C. Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfuntion and previous heart failure symptoms. J Am Coll Cardiol. 2008; 52:1834-43.
15. Abraham WT, Young JB, Leon AR, Adler S, Bank AJ, Hall SA, Lieberman R, Liem LB, O’Connell JB, Schroeder JS, Wheelan KR. Effects of cardiac resynchronization on disease progression in patients with left ventricular systolic dysfunction, an indication for an implantable cardioverter-defibrillator, and mildly symptomatic chronic heart failure. Circulation. 2004; 110:2864-8.
16. Beshai JF, Grimm RA, Nagueh SF, Baker JH 2nd, Beau SL, Greenberg SM, Pires LA, Tchou PJ. Cardiac-resynchronization therapy in heart failure with narrow QRS complexes. N Engl J Med. 2007: 357:2461-71.
17. Thibault B, Harel F, Ducharme A, White M, Ellenbogen KA, Frasure-Smith N, Roy D, Philippon F, Dorian P, Talajic M, Dubuc M, Guerra PG, Made L, Rivard L, Andrade J, Khairy P, LESSER-EARTH Investigators. Cardiac resynchronization therapy in patients with heart failure and a QRS complex < 120 milliseconds: The evaluation of resynchronization therapy for heart failure (LESSER-EARTH) trial. Circulation. 2013; 127:873-81.
18. Linde C, Ledercq C, Rex S, Garrigue S, Lavergne T, Cazeau S, McKenna W, Fitzgerald M, Deharo JC, Alonso C, Walker S, Braunschweig F, Bailleul C, Daubert JC. Long-term benefits of biventricular pacing in congestive heart failure: results from the multisite stimulation in cardiomyopathy study (MUSTIC) study. J Am Coll Cardiol. 2002; 40:111-8.
19. Brignole M, Botto G, Mont L, Iacopino S, De Marchi G, Oddone D, Luzi M, Tolosana JM, Navazio A, Menozzi C. Cardiac resynchronization therapy in patients undergoing atrioventricular junction ablation for permanent atrial fibrillation: a randomized trial. Eur Heart J. 2011; 32:2420-9.
2. Shea JB, Sweeney MO. Cardiac resynchronization therapy: a patient’s guide. Circulation. 2003;108:e64-6.
3. Bui AL, Horwich TB, Fonarow GC. Epidemiology and risk profile of heart failure. Nat Rev Cardiol. 2011; 8(1):30-41.
4. Washington Heart Rhythms Associates. CRT Figures 1 and 2 (cited 2015 May 22). Available from http://www.washingtonhra.com/pacemakers-icds/cardiac-resynchronization-therapy-crt.php
5. Budzikowski AS, Gabriels JK. Cardiac resynchronization technique. Medscape (article online). 2014. (Cited 2015 May 22). Available from http://emedicine.medscape.com/article/1839506-technique
6. Brignole M, Auricchio A, Baron-Esquivias G, Bordachar P, et al. 2013 ESC guidelines on cardiac pacing and cardiac resynchroniztion therapy. Eur Heart J. 2013;34:2281-2329.
7. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, Tavazzi L. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005; 352:1539-49.
8. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, Carson P, DiCarlo L, DeMets D, White BG, DeVries DW, Feldman AM. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004; 350:2140-50.
9. Cazeau S, Leclercq C, Lavergne T, Walker S, Farma C, Linde C, Garrigue S, Kappenberger L, Haywood GA, Santini M, Baileul C, Daubert JC. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Engl J Med. 2001; 344:873-80.
10. Auricchio A, Stellbrink C, Butter C, Sack S, Vogt J, Misier AR, Bocker D, Block M, Kirkels JH, Kramer A, Huvelle E. Clinical efficacy of cardiac resynchronization therapy using left ventricular pacing in heart failure patients stratified by severity of ventricular of conduction delay. J Am Coll Cardiol 2003; 42:2109-16.
11. Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E, Kocovic DC, Packer M, Clavell AL, Hayes DL, Ellestad
M, Trupp RJ, Underwood J, Pickering F, Truex C, McAtee P, Messenger J. Cardiac resynchronization in chronic heart failure. N Engl J Med. 2002; 346:1845-53.
12. Moss AJ, Hall Wj, Cannom DS, Klein H, Brown MW, Daubert JP, Estes NA 3rd, Foster E, Greenberg H, Higgins SL, Pfeffer MA, Solomon SD, Wilber D, Zareba W. Cardiac-resynchronization therapy for the prevention of heart failure events. N Engl J Med. 2009; 361:1329-38.
13. Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S, Hohnloser SH, Nichol G, Birnie DH, Sapp JL, Yee R, Healey JS, Rouleau JL. Cardiac-resynchronization therapy for mild-to-moderate heart failure. N Engl J Med. 2010; 363:2385-95.
14. Linde C, Abraham WT, Gold MR, ST John Sutton M, Ghio S, Daubert C. Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfuntion and previous heart failure symptoms. J Am Coll Cardiol. 2008; 52:1834-43.
15. Abraham WT, Young JB, Leon AR, Adler S, Bank AJ, Hall SA, Lieberman R, Liem LB, O’Connell JB, Schroeder JS, Wheelan KR. Effects of cardiac resynchronization on disease progression in patients with left ventricular systolic dysfunction, an indication for an implantable cardioverter-defibrillator, and mildly symptomatic chronic heart failure. Circulation. 2004; 110:2864-8.
16. Beshai JF, Grimm RA, Nagueh SF, Baker JH 2nd, Beau SL, Greenberg SM, Pires LA, Tchou PJ. Cardiac-resynchronization therapy in heart failure with narrow QRS complexes. N Engl J Med. 2007: 357:2461-71.
17. Thibault B, Harel F, Ducharme A, White M, Ellenbogen KA, Frasure-Smith N, Roy D, Philippon F, Dorian P, Talajic M, Dubuc M, Guerra PG, Made L, Rivard L, Andrade J, Khairy P, LESSER-EARTH Investigators. Cardiac resynchronization therapy in patients with heart failure and a QRS complex < 120 milliseconds: The evaluation of resynchronization therapy for heart failure (LESSER-EARTH) trial. Circulation. 2013; 127:873-81.
18. Linde C, Ledercq C, Rex S, Garrigue S, Lavergne T, Cazeau S, McKenna W, Fitzgerald M, Deharo JC, Alonso C, Walker S, Braunschweig F, Bailleul C, Daubert JC. Long-term benefits of biventricular pacing in congestive heart failure: results from the multisite stimulation in cardiomyopathy study (MUSTIC) study. J Am Coll Cardiol. 2002; 40:111-8.
19. Brignole M, Botto G, Mont L, Iacopino S, De Marchi G, Oddone D, Luzi M, Tolosana JM, Navazio A, Menozzi C. Cardiac resynchronization therapy in patients undergoing atrioventricular junction ablation for permanent atrial fibrillation: a randomized trial. Eur Heart J. 2011; 32:2420-9.
Published
2016-05-02
Views & Downloads
Abstract views: 3584
PDF downloads: 2743
PDF downloads: 2743
How to Cite
Amin, H., & Danny, S. (2016). Cardiac Resynchronization Therapy in Heart Failure Management. Indonesian Journal of Cardiology, 36(4), 227-36. https://doi.org/10.30701/ijc.v36i4.506
Section
Review Article
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
